Effect of fractional blood flow on plasma skimming in the microvasculature

摘要

Although redistribution of red blood cells at bifurcated vessels is highlydependent on flow rate, it is still challenging to quantitatively express thedependency of flow rate in plasma skimming due to nonlinear cellularinteractions. We suggest a plasma skimming model that can involve the effect offractional blood flow at each bifurcation point. For validating the new model,it is compared with \textit{in vivo} data at single bifurcation points, as wellas microvascular network systems. In the simulation results, the exponentialdecay of plasma skimming parameter, $M$, along fractional flow rate shows thebest performance in both cases.